The UK, the main stock index fell in early trading, weighed down by falls in major mining and oil stocks.
The FTSE 100 fell below 7,400 points, the shedding of a drop of 31 points, or 0.4%, at 7,383.13.
The biggest losers have been the mining companies including Glencore and Rio Tinto, with oil giants BP and Shell.
It is after further falls in global oil and commodity prices, the Brent crude oil extend its losses and falling nearly 1% to $61.65 a barrel.
The price of oil has also fallen heavily on Tuesday on the warnings of the International Energy, the combination of slowing demand and rising inventories.
Royal Dutch Shell shares were down 1.5% to 2396.50 pence Wednesday morning, while BP was less than 1% to 498.10 pence.
Glencore, Rio Tinto and Anglo American were each down over 2% on the back of the fall in metal prices.
But gold miner Fresnillo was the biggest winner on the index, up 2.8% after the gold price edged 0.3% higher to $1,284.$ 30 per ounce.