Cell JCVI-syn3.0, the genome of which consists of 473 genes
A group of scientists led by geneticist Craig Venter has succeeded in creating a synthetic bacterial cell, the genetic code which consists of 473 gene. The existence in nature of a living being with less genetic code and is able to be parasitic by unknown, it follows from article the authors of the study in the journal Science.
The study was conducted jointly by researchers at the California Institute of Craig Venter and Synthetic Genomics. The basis at the beginning of the work, the researchers took the bacteria Mycoplasma mycoides (JCV-syn1.0), the genome of which consists of 901 gene. They broke the genetic code into eight segments, and then began to make various combinations, to check to what extent you can reduce its genome so that the cell is not killed. As a result the method of selection they managed to exclude the source of an organism’s genome 428 genes that were not necessary for its independent existence.
As a result, scientists found that the cell is able to survive with the genetic code of the 473 genes. The final genome of the organism in 31% of the necessary for the survival of the genes, the biological function of which scholar is not identified, according to the study.
In nature there are parasites, with a minimum of 473 genes, but they cannot exist independently.
The new body received the name of JCV-syn3.0. The authors of this study applied for the patenting of methods used in the work.
These studies will contribute to predictable outcomes further the work of creating synthetic organisms, are on the SGI website the words of one of the authors of the study, Dr. Daniel Gibson.